Age group most affected by hyperglycaemia in HIV patients on Dolutegravir ART regimen receiving care at Jinja Regional Referral Hospital. A cross-sectional study.
DOI:
https://doi.org/10.51168/314qa284Keywords:
Effective ART regimens, Noncommunicable diseases among PLWH, Hyperglycaemia screeningAbstract
Background: The emergence of non communicable diseases among people receiving ART has raised concerns as to whether demographic characteristics like Age can increase the chances of developing hyperglycaemia among HIV patients on effective ART regimens. The aim of this study is to determine the age group most affected by Hyperglycaemia in HIV patients on DTG based ART regimen.
Methodology: A cross-sectional hospital-based study. The study population included all adult PLWHIV initiated on Dolutegravir based ART regimen attending ART clinic at JRRH in Eastern Uganda. The total respondents were 96. Both male and female were included
Results: The most affected age group was 46-60years with hyperglycaemia prevalence of 47.4%. majority 45(46.9%) of the respondents were in the age group of 46-60years with hyperglycaemia prevalence of 9(47.4%). 31-45years were 30(31.2%) with hyperglycaemia prevalence of 4(21.0%). 18-30years were 18(18.8%) with their prevalence of hyperglycaemia being 3(15.8%) and the minority of the respondents 3(3.1%) were above 60years with hyperglycaemia prevalence of 3(15.8%). Concerning respondents’ occupation, majority 37(38.5%) had private business, followed by civil servants who were 31(32.3%), followed by unemployed who were 25(26.0%) and the minority 3(3.1%) were healthcare workers.
Conclusion: Older age showed a slightly higher risk of developing of hyperglycaemia among PLWH with younger age groups showing a slightly lower prevalence of hyperglycaemia.
Recommendation: Hyperglycaemia screening and monitoring should be done for patients taking Dolutegravir as well sensitizing all age groups about healthy living to reduce chances to developing hyperglycaemia and other non communicable diseases among PLWH.
References
1. Lamorde M, Atwiine M, Owarwo NC, et al. Dolutegravir associated hyperglycemia in patients with HIV. Lancet HIV 2020; 7(7): 461–462
2. Hailu W, Tesfaye T, Tadesse A. Hyperglycemia after dolutegravir-based antiretroviral therapy. Int Med Case Rep J. 2021; 14:503–7.
3. Mugoya, A., & Ogwal, I. A. (2024). PREVALENCE OF HYPERGLYCEMIA IN HIV PATIENTS ON DOLUTEGRAVIR ART REGIMEN RECEIVING CARE AT JINJA REGIONAL REFERRAL HOSPITAL. A CROSS-SECTIONAL STUDY. SJ Diabetes, Hypertension and Cancer Research Africa, 1(6), Article 6. https://doi.org/10.51168/5pb0y162
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Copyright (c) 2026 Annet Mugoya , Ivan Awach Ogwal (Author)

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